V Día de la Investigación Clínica

Dr. José Sánchez
Dra. Cristina Alenda
Dr. Juan Carlos Rodríguez
Dr. Enrique de Madaria
Dr. Óscar Moreno
Dña. Elena Bertomeu
D. Andreu Campos
Dr. Pascual Marco
Dr. José María Palazón
Dr. Jesús Rodríguez
Dr. Félix Lluis Casajuana
Dra. Paloma Vela
Comisión de Investigación
Comité de Evaluación

José Antonio Mas
Ana Tobarra
Alberto García
Guillem Sáez
Miguel Tirado
Héctor Sebastián
Samanta Ortuño
Ana Obispo

Modera: Pascual Marco Vera. Coordinador del Grupo “Investigación en Hematología y Hematoterapia”.

1. José Miguel Castro. Angio-TC pulmonar durante la pandemia de COVID-19: comparación en pacientes con y sin la infección y con una serie prepandémica.
2. Lucía Guilabert. Coronavirus Disease Transmission Prevented in an Endoscopy Unit with Universal Protective Measures and No Systematic Preprocedural Testing.
3. Natali Jiménez. The Waning of BNT162b2 Vaccine Effectiveness for SARS-CoV2 Infection Prevention over Time: A Test-Negative Study in Health Care Professionals of a Health Department from January 2021 to December 2021.
4. Laura Torres. Association between Dietary Diversity and All-Cause Mortality: A Multivariable Model in a Mediterranean Population with 18 Years of Follow-Up.
5. Adrián Viudez. Effectiveness and safety of erenumab and galcanezumab in the prevention of chronic and episodic migraine: A retrospective cohort study.

Modera: José María Palazón. Investigador Emérito de ISABIAL.

6. Cristina Alenda. xDEEP-MSI: Explainable Bias-Rejecting Microsatellite Instability Deep Learning System in Colorectal Cancer.
7. Silvia Delgado. Biospia del ganglio centinela y disección axila dirigida en mujeres con cáncer de mama y axila positiva en el momento del diagnóstico: caminando hacia el futuro.
8. Héctor Pinargote. Mild SARS-CoV-2 infection in vulnerable patients: implementation of a clinical pathway for early treatment.
9. Mariano Andrés Collado. Birefringent crystals deposition and inflammasome expression in human atheroma plaques by levels of uricemia.
10. Vicente Ignacio Arrarte. Early carbohydrate antigen 125 as a mortality predictor in hospitalized patients with coronavirus disease 2019.
11. José Ignacio Cameo. Evolution of the emotional impact in patients with early inflammatory bowel disease during and after Covid-19 lockdown.
12. Pablo Chico. The effectiveness of mRNA vaccines to prevent SARS-CoV-2 infection and hospitalisation for COVID-19 according to the time elapsed since their administration in health professionals in the Valencian Autonomous Community (Spain).
13. Laura María Compañ. Association between the Use of Folic Acid Supplements during Pregnancy and Children’s Cognitive Function at 7-9 Years of Age in the INMA Cohort Study.
14. Mónica Escorial. Sex-Differences in Pain and Opioid Use Disorder Management: A Cross-Sectional Real-World Study.
15. Celia García. Concordance of the filmarray blood culture identification panel 2 and classical microbiological methods in a bacteriemia diagnostic unit.

Modera: Jesús Rodríguez. Investigador Emérito de ISABIAL.

16. Ignacio Gayá. Mosaic attenuation in non-fibrotic areas as a predictor of nonusual interstitial pneumonia pathologic diagnosis.
17. Pilar González de la Aleja. Impact of COVID19 pandemic on the incidence of health-care associated Clostridioides difficile infection.
18. Paula Gras. Estimated Costs Associated with Surgical Site Infections in Patients Undergoing Cholecystectomy.
19. Javier Muriel. Long-term deprescription in chronic pain and opioid use disorder patients: Pharmacogenetic and sex differences.
20. Alejandro Oncina. Self-reported health status and mortality from all-causes of death, cardiovascular disease and cancer in an older adult population in Spain.
21. Eliseo Pascual. Agreement among multiple observers on crystal identification by synovial fluid microscopy.
22. Ana Peiró. Sex Differences in Oxycodone/Naloxone vs. Tapentadol in Chronic Non-Cancer Pain: An Observational Real-World Study.

Breve descanso.

• D. Miguel Ángel García. Gerente del Departamento de Salud de Alicante – Hospital General, Presidente de la Junta de Gobierno y Vicepresidente del Patronato de la Fundación para la Gestión de ISABIAL.
• Dña. Cristina Alenda. Subdirectora Científica de ISABIAL.
• Dña. Concha Andrés. Secretaria autonómica de Eficiencia y Tecnología Sanitaria. Vocal del Patronato de la Fundación para la Gestión de ISABIAL.
• Dña. Maribel Beltrán. Directora del Secretariado para la Investigación de la Universidad de Alicante.

Modera: Félix Lluis. Investigador Emérito de ISABIAL.

23. José Manuel González. Absent in Melanoma 2 (AIM2) Regulates the Stability of Regulatory T Cells.
24. Sandra González. Olive oil consumption and all-cause, cardiovascular and cancer mortality in an adult mediterranean population in Spain.
25. Anabel García. Mutational signature profiling classifies subtypes of clinically different mismatch-repair-deficient tumours with a differential immunogenic response potential.
26. Enrique de Madaria. Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis.
27. Carolina Mangas. Factors associated with lesion detection in colonoscopy among different indications.
28. Agustín Manresa. Heart Rate Variability-Guided Training for Improving Mortality Predictors in Patients with Coronary Artery Disease.
29. María Teresa Marcos. 3-Year Outcomes of XEN Implant Compared With Trabeculectomy, With or Without Phacoemulsification for Open Angle Glaucoma.
30. Rodrigo Jover. Risk of Colorectar Cancer and Advanced Polyps One Year After Excision of Higf-Risk Adenomas.

Modera: Paloma Vela. Coordinadora del Grupo “Investigación en Enfermedades Reumáticas y Autoinmunes”.

31. Paola Melgar. Textbook outcome among patients undergoing enhanced recovery after liver transplantation stratified by risk. A single-center retrospective observational cohort study.
32. Luis Moral. Management of parapneumonic pleural effusion and empyema in children: A tale of two cities.
33. Sergio Ortiz. Early postoperative complications after gastric bypass revisional surgery in patients with previous sleeve gastrectomy versus primary gastric bypass.
34. Judit Parra. Prediction of peritoneal soiling in acute appendicitis with simple clinical and laboratory data. Prospective, multicenter, cohort study of 2,645 adult patients nationwide.
35. Nikiben Patel. A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair.
36. Paula Piñero. Identification of Leukemia-Associated Immunophenotypes by Databaseguided Flow Cytometry Provides a Highly Sensitive and Reproducible Strategy for the Study of Measurable Residual Disease in Acute Myeloblastic Leukemia.
37. Bernat Soria. Phase I dose-escalation single centre clinical trial to evaluate the safety of infusion of memory T cells as adoptive therapy in COVID-19 (RELEASE).
38. Juan Carlos Trujillo. Machine learning model from a Spanish cohort for prediction of SARS-COV-2 mortality risk and critical patients.
39. Juan Carlos Rodríguez. Nasopharyngeal Microbiota as an early severity biomarker in COVID-19 hospitalised patients.

Votación de las mejores presentaciones en cada categoría y entrega de diplomas a los ganadores.

• Enrique de Madaria. Subdirector Científico para Proyectos de ISABIAL.
• Luis Mena. Director Médico del Hospital General Universitario Dr. Balmis y Presidente de la Comisión de Investigación de ISABIAL.